ribosome@gentoo.org Olivier Fisette sci A protein families and domains database maintained at the Swiss Institude for Bioinformatics. It consists of biologically significant sites, patterns and profiles that help to reliably identify to which known protein family (if any) a new sequence belongs. PROSITE currently contains patterns and profiles specific for more than a thousand protein families or domains. Each of these signatures comes with documentation providing background information on the structure and function of these proteins.